``html Avatrombopag is available in two dosage forms: tablets and granules for oral administration. Its storage conditions directly affect the stability and effectiveness of the drug. Proper storage is the main guarantee of the safety and effectiveness of medicines for patients.
I. General storage conditions and requirements
1. Temperature control
Both Avatrombopag tablets and granules for oral administration should be stored at room temperature in the range from 20 °C to 25 °C. Short-term temperature fluctuations from 15°C to 30°C are allowed. Avoid storing the drug in high temperature conditions, for example, in summer in closed cars, near radiators or on window sills exposed to the sun.
2. Storage in the original packaging
Tablets should be stored in their original packaging (blister) and not transferred to other containers. The original packaging has good moisture-proof properties, which effectively protects the quality of the drug. After each dose, return the remaining medicine to its original packaging and store it properly.
3. Choosing a storage location
Keep the drug out of the reach of children. Do not store it in places with high humidity, such as bathrooms or near kitchen sinks. Choose a cool, dry, and dark place, such as a bedroom or closet. Do not store the product together with volatile substances or objects with a strong odor.
ii. Special recommendations for the storage of various dosage forms
1. Tablet storage
Avatrombopag tablets are packed in cardboard packages. Keep the blister safe and avoid squeezing or puncturing the aluminum foil. When taking a dose, tear along the opening, remove one tablet and immediately store the remaining portion properly. Do not remove the tablets from the blister pack or place them in the tablet box for long-term storage.
2. Storage of granules for oral administration
Avatrombopag granules for oral administration are supplied in the form of capsules of 10 mg each. Capsules should be stored intact in their original packaging with a tightly closed lid to prevent moisture ingress. Do not remove the granules and store them separately; the capsule should only be opened immediately before use.
iii. Shelf life and waste management
1. Expiration date management
Before taking each dose, check the expiration date on the package. Do not use expired medicines, as the active ingredients may deteriorate, even if the appearance does not change. Regularly clean up your medicine cabinet and remove medicines that are about to expire in a timely manner to ensure their safety.
2. Shelf life after cooking
To take the granules inside, open the capsule and mix the contents with soft food or liquid immediately before administration. The mixture should be taken immediately after preparation and cannot be stored for future use. This is a special requirement for the storage of pellets, which differs significantly from the usual storage of whole capsules.
3. Waste disposal
Empty capsule shells can be disposed of in household garbage. Consult with your pharmacist about appropriate disposal methods for expired or unused medicines to avoid accidental release to the environment. The blister packaging materials should be disposed of properly.
